For laboratory research purposes only. Not for human consumption.
MOTS-C
Product Overview
MOTS-C 20mg is offered by Healthy Peps as a laboratory research mitochondria-derived peptide. This product is supplied in lyophilized form at ≥99% purity and is intended strictly for in vitro and laboratory research purposes only. Not for human or veterinary consumption.
This product is supplied in lyophilized powder and is packaged in sealed, laboratory-grade vials. Review the current batch report to confirm identity, content and analytical purity. A catalogue specification is not a batch-specific test result.
This product is not intended for human or veterinary consumption. For laboratory and research use only.
Buy MOTS-C 20 mg in Canada — Mitochondria-Derived Research Peptide
MOTS-C 20 mg is supplied by Healthy Peps as a lyophilized mitochondria-derived peptide for metabolic signalling research, shipped from Canada with batch documentation.
Reference Data
- Compound
- MOTS-c (mitochondrial open reading frame of the 12S rRNA-c)
- CAS Number
- 1627580-64-6
- Sequence
- 16 amino acids — Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Reported Molecular Weight
- ≈ 2,175 Da
- Appearance
- White lyophilized powder
- Solubility (lab)
- Water, saline, bacteriostatic water
- Vial Format
- 20 mg per vial
- Storage
- −20 °C lyophilized, protected from light
Research Context
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA region, placing it in the small but growing class of mitochondrially derived peptides. The foundational characterisation by Lee and colleagues in Cell Metabolism (2015) described it as a regulator of metabolic homeostasis acting through the AMPK pathway, with reported effects on glucose metabolism and stress-response signalling in cell and animal models.
Its research appeal is mechanistic: MOTS-c is one of the few peptides studied as a retrograde mitochondrial signal — a molecule produced by the mitochondrion that influences nuclear gene expression. That makes it a recurring subject in metabolic-adaptation research, including exercise-mimetic and insulin-sensitivity study designs.
In vitro, MOTS-c is used in AMPK-activation assays, mitochondrial stress and respiration models, and metabolic pathway screens in cultured cells. Because the sequence is short and well defined, analytical verification by HPLC and mass spectrometry is unambiguous, and batch documentation reports a single-peak purity result.
The 20 mg format suits laboratories running repeated metabolic assays from a single documented batch.
Selected Reading & Research Notes
- Lee et al. (2015): The mitochondrial-derived peptide MOTS-c — Primary experimental research on metabolic signaling in preclinical models. Findings do not establish human use or validate a supplied batch.
Citations are provided for research orientation only. Healthy Peps does not claim that any cited finding applies to this material, and published results should be independently verified before use in a protocol.
Laboratory Handling
Reconstitute in bacteriostatic water or the diluent specified by your protocol, adding it slowly against the vial wall and swirling gently. Avoid vortexing, which can shear peptide chains. Keep reconstituted solutions refrigerated and within your protocol window; store lyophilized vials at −20 °C protected from light.
How It Differs From Related Compounds
MOTS-c is not a receptor agonist in the incretin or GH-axis families. Its research mechanism — AMPK-pathway activation downstream of a mitochondrial signal — gives it a distinct place in metabolic study designs, which is why it is normally run as its own experimental arm rather than as a substitute for other peptides on this catalogue.
MOTS-C — Buyer Questions
Products sold by Healthy Peps are intended strictly for laboratory research use only. They are not intended for human consumption and are not intended to diagnose, treat, cure, or prevent any disease. Healthy Peps does not provide medical advice.
Customer Reviews
Fast shipping, good product
Ordered Monday, had it by Thursday in Saskatoon. Reconstituted cleanly and confirmed bioactivity. Great experience.
Kate B.
Reproduced published data
Was able to reproduce key findings from a paper I'd been trying to replicate. That tells you the quality is on point.
Luke M.
Stable and active
This stuff has maintained activity through my whole study period. Properly handled.
Rach L.
Verified by mass spec
I have access to mass spec through my lab and checked this. Molecular weight is correct, it's genuine MOTS-C.
Joe F.
My regular order
This has become a regular in my order. Reliable, consistent, and the documentation is thorough. Makes planning so much easier.
Sara N.
Can't complain
Good product, fair price, fast shipping, verifiable COA. Everything you'd want. Quality stuff.
Cam T.
Good but keep it stocked
When it's available it's excellent. Problem is it sells out sometimes. I try to order extra when I can. Quality is never an issue.
Dan R.
Working great
Getting clean, reproducible data. The peptide is clearly well made. Shipping to Halifax was fast too.
Amy C.
Finally found good MOTS-C
MOTS-C is hard to find in good quality. Most places don't carry it or the stuff is questionable. This is genuine.
Pat O.
Solid but pricey
Excellent quality, no doubt. A bit on the expensive side but you get what you pay for. I'd rather pay more for good stuff.
Ben G.
Great MOTS-C
Been looking for a reliable source for a while. This is it. Clean, active, and consistent across batches. COA is verifiable.
Greg S.
Third order, all consistent
Three orders and every batch the same. That tells me the manufacturing is solid. MOTS-C that performs the same every time is hard to find.
Mel J.
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